Tesamorelin 10 mg Product Information
Tesamorelin 10 mg research-grade lyophilized peptide powder in a glass vial. Tesamorelin (also known as TH9507) is a synthetic analog of human Growth Hormone-Releasing Hormone (GHRH), studied in experimental models of GH/IGF-1 axis modulation, visceral adiposity, lipodystrophy-like states and metabolic regulation. Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use. Purity 99%+ (HPLC, third-party tested) Form Lyophilized peptide powder Content 10 mg Tesamorelin per vial Packaging Glass vial with sterile closure Storage Store lyophilized at 2–8 °C in a dry, desiccated place, protected from light. Molecular formula C221H366N72O67S Molecular weight ~5135.8 g·mol⁻¹ Sequence (trans-3-hexenoyl)-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 CAS number 218949-48-5 In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC). For a compatible research-only solvent, see Bacteriostatic water – 10 ml . Research Overview Tesamorelin (TH9507) is a synthetic peptide analog of human Growth Hormone-Releasing Hormone (GHRH) comprising the full 44-amino acid sequence of hGHRH with an N-terminal trans-3-hexenoyl modification that enhances stability and resistance to enzymatic degradation. In experimental systems, Tesamorelin is used as a tool compound to investigate regulation of the GH/IGF-1 axis, visceral adipose tissue dynamics, lipodystrophy-like phenotypes and broader metabolic and neuroendocrine pathways in vitro and in vivo research models. Primary Research Areas GH/IGF-1 axis and pituitary signaling: Used in experimental models to study how GHRH analog stimulation influences pituitary growth hormone release, circulating IGF-1 levels and downstream anabolic and metabolic signaling cascades. Visceral adipose tissue and lipodystrophy models: Applied in preclinical research exploring alterations in visceral fat depots, abnormal fat distribution and associated metabolic parameters in lipodystrophy-like experimental paradigms. Metabolic regulation and glucose–lipid interactions: Employed to probe relationships between GH/IGF-1 signaling, glucose handling, lipid metabolism and insulin sensitivity in diverse metabolic research models. Body composition and tissue remodeling: Used in studies of lean mass, fat mass and tissue remodeling to characterize how chronic modulation of the GHRH–GH–IGF-1 axis impacts body composition in experimental systems. Neuroendocrine and cognitive research: Investigated in models assessing hypothalamic–pituitary regulation, neuroendocrine feedback loops and potential cognitive or brain-structure–related endpoints in aging or metabolic-stress paradigms.
