GHK Basic Product Information
GHK-Cu peptide , also referred to as GHK base or GHK basic, is a naturally occurring tripeptide composed of glycine, histidine, and lysine that is extensively examined in laboratory research for its involvement in cellular signaling pathways and tissue-associated regulatory processes in non-human experimental models. Due to its endogenous origin and conserved structure, GHK is frequently included in studies exploring cellular communication, matrix-associated signaling, and pathway coordination linked to tissue organization. In controlled laboratory studies, GHK demonstrates a high affinity for copper ions, forming the well-characterized GHK-Cu complex, which is investigated for its role in oxidative stress–associated signaling, protein synthesis pathways, and gene-expression modulation. Research models examining GHK and GHK-Cu frequently focus on sequence-driven transcriptional activity, extracellular matrix–adjacent signaling, and inflammation-associated regulatory networks in non-human test systems. The peptide’s low molecular weight and structural simplicity support its inclusion in research models evaluating cellular uptake dynamics, intracellular signaling coordination, and stress-response pathway behavior. As a result, GHK is widely studied in longevity-adjacent research, surface-associated signaling models, and tissue-resilience investigations conducted strictly within laboratory environments. GHK vs. GHK-Cu in Research Context GHK-Cu represents a metal-bound form of GHK, where copper coordination alters the peptide’s biochemical interaction profile and signaling behavior in experimental systems. Research comparing GHK and GHK-Cu focuses on differences in gene-expression patterns, oxidative signaling frameworks, and protein interaction dynamics, allowing investigators to select the appropriate form based on experimental design parameters rather than applied outcomes. As a versatile research peptide, GHK basic continues to serve as a valuable tool for investigating cellular regulation, matrix-associated signaling, and tissue-organization pathways in non-human laboratory models, contributing to a deeper understanding of peptide-mediated biological signaling architectures. Summary of Characteristics Characteristic Details Chemical Sequence of Amino Acids Glycine-Histidine-Lysine CAS Number 49557-75-7 Molecular Formula C14H24N6O4 Molecular Weight 340.4 g/mol Other Known Titles GHK Research Peptide, Gly-His-Lys Tripeptide, GHK Basic, GHK Base
